TABLE 4

pH regulates sexual mating in C. albicansa

MediumMating efficiency at pH:
4.05.06.07.08.0
Lee's glucose
    Solid(6.3 ± 1.2) × 10−2(1.0 ± 0.2) × 10−1(1.7 ± 0.3) × 10−1*(5.9 ± 0.4) × 10−2(3.1 ± 0.8) × 10−2
    Liquid(5.6 ± 3.9) × 10−5(3.5 ± 1.5) × 10−4(1.9 ± 1.2) × 10−3(5.2 ± 1.4) × 10−2(2.4 ± 0.2) × 10−1*
SCD
    Solid(2.6 ± 0.7) × 10−1(1.6 ± 0.3) × 10−1(3.4 ± 0.7) × 10−1(7.8 ± 1.7) × 10−1*(5.5 ± 3.0) × 10−1
    Liquid(3.9 ± 4.6) × 10−5(5.1 ± 1.0) × 10−2(1.3 ± 0.2) × 10−1(1.9 ± 0.4) × 10−1*(5.8 ± 1.6) × 10−2
  • a Opaque cells of SZ306u (an a strain) and GH1349 (an α strain) were mixed and used for quantitative mating assays (see the Materials and Methods section). *, the mating efficiency was statistically significantly (Student's t test, P < 0.05) higher than that under the lower-pH conditions.