TABLE 1

List of yeast and mammalian homologs of HR players

CategoryHomolog(s) in:
YeastMammal
5′ to 3′ nucleasesMRXMRN
Mre11, Rad50, Xrs2Mre11, Rad50, Nbs1
Sae2CtIP
RecQ helicasesSgsIBLM, WRN
RAD51 mediatorsRAD52BRCA2, RAD51 paralogs