Table 2

sMICs of amphotericin B in the presence and absence of DNasea

StrainsMIC (mg/liter) at 8 hFCsMIC (mg/liter) at 12 hFCsMIC (mg/liter) at 24 hFCsMIC (mg/liter) at 48 hFC
−DNase+DNase−DNase+DNase−DNase+DNase−DNase+DNase
Af2930.06250.062510.06250.062510.1250.03125410.1258
YHCF10.0150.01510.0310.01520.1250.01563810.1258
YHCF20.1250.12510.1250.03120.1250.01563820.12516
YHCF30.0310.01520.06250.01520.1250.007811610.062516
YHCF40.0310.031111110.25440.2516
YHCF50.0070.00710.250.25110.25440.2516
  • a Biofilms were treated with amphotericin B in the presence of 128 mg/liter of DNase (+DNase) or in the absence of DNase (−DNase). FC, fold change in MIC relative to control.