Table 3.

Conserved genes from filamentous fungi containing RFX consensus binding sites

OrganismGenePosition of binding siteaPosition in P. marneffei homologaPutative function
A. fumigatusAFUA_7G05950−609 (−)−542 (−)Cytokinesis EF hand protein (Cdc4)
A. nidulansAN6732.3−388 (−), −534 (−)
A. oryzaeAO090005000459−577 (−)
A. terreusATEG_063406−483 (−)
A. fumigatusAFUA_3G10250−348 (−), −967 (−)−318 (−)Similarity to protein kinase (Cdc15) regulating the mitotic exit network
A. nidulansAN4963.3−291 (+/−)
A. oryzaeAO090003000564−374 (+/−)
A. terreusATEG_04556−338 (+/−)
A. fumigatusAFUA_2G03150−326 (+/−)−305 (−)Related to kinesin protein (KipB) involved in mitotic-spindle dynamics
A. nidulansAN4513.3 (kipB)−272 (+/−), −570 (−)
A. oryzaeAO090120000272−327 (+)
A. terreusATEG_09578−262 (+), −316 (+/−)
A. fumigatusAFUA_6G08120−246 (+)−250 (+/−)Similarity to protein kinase (SldA/Bub1) regulating the spindle assembly checkpoint
A. nidulansAN3946.3−253 (+), −311 (+)
A. oryzaeAO090003000118−230 (−)
A. terreusATEG_05847−207 (+)
A. fumigatusAFUA_5G09710−147 (−)−150 (+)Related to separin protein (BimB) involved in chromatid segregation and DNA repair
A. nidulansAN8783.3 (BimB)−131 (−)
A. oryzaeAO090005000276−156 (−)
A. terreusATEG_06440−159 (−)
A. fumigatusAFUA_2G12390−619 (+)−352 (−), −367 (−), −481 (+)Maintenance of ploidy protein kinase (Mob1)
A. nidulansAN6288.3−195 (+), −491 (+)
A. oryzaeAO090026000371−497 (+)
A. terreusATEG_01172−525 (+)
A. fumigatusAFUA_3G08100−234 (+), −668 (−)−222 (−)Spindle checkpoint kinase (Mph1)
A. nidulansAN2927.3−247 (−)
A. oryzaeAO090005001468−145 (−), 206 (+)
A. terreusATEG_01659−200 (+)
A. fumigatusAFUA_6G02670−262 (+/−)−766 (−)G2-specific protein kinase (NimA)
A. nidulansAN9504.3−242 (+/−), −328 (−)
A. oryzaeAO090120000152−255 (+/−)
A. terreusATEG_07188−268 (+/−)
A. fumigatusAFUA_6G08530−244 (−)−267 (−), −639 (+)Sister chromatid separation protein (Src1)
A. nidulansAN3910.3−208 (−)
A. oryzaeAO090001000513−167 (−)
A. terreusATEG_05798−181 (−)
  • a Relative to ATG. +, plus strand; −, minus strand.