TABLE 1.

TbPRMT5-TAP-associated proteins identified by mass spectrometry

Locus tagName/descriptionMolecular mass (kDa)Molecular functionaBiological processa
Tb09.160.4250TRYP1; tryparedoxin peroxidase22.4Trypanothione-disulfide reductase activity (ISS)Electron transport (ISS)
Tb10.61.2130ATP-dependent DEAD/H RNA helicase; putative71.3ATP binding (IEA, ISS); ATP-dependent helicase activity (IEA, ISS); nucleic acid binding (IEA)Nucleobase, nucleoside, nucleotide, and nucleic acid metabolism (ISS)
Tb10.389.1040Hypothetical protein; no conserved domains121.2Nucleic acid binding (IEA)Unknown
Tb09.160.1400Hypothetical protein; no conserved domains147.2UnknownUnknown
  • a T. brucei GeneDB Gene Ontology evidence codes: IEA, inferred by electronic annotation; ISS, inferred from sequence or structural similarity.