Ascomycete proteins that have orthologs in D. bruxellensis but not S. cerevisiae

Functional class and NCBI accession no.SpeciesGene nameFunction
Nitrate metabolism
    CAA11229 Hansenula polymorpha YNT1 Nitrate transporter
    CAA11232 Hansenula polymorpha YNR1 Nitrate reductase
    CAA11230 Hansenula polymorpha YNI1 Nitrite reductase
    CAA11231 Hansenula polymorpha YNA1 Nitrate assimilation pathway-specific Zn(II)2Cys6 transcription factor
    CAC16081 Hansenula polymorpha YNA2 Nitrate assimilation pathway-specific Zn(II)2Cys6 transcription factor
Metabolism of alternative carbon sources
    AAX31178 Candida albicans NAG1 Glucosamine-6-phosphate deaminase
    CAH02587 Kluyveromyces lactis LAC4 β-Galactosidase
    CAE47547 Ambrosiozyma monospora ALX1 l-Xylulose reductase
    CAG88556a Debaryomyces hansenii Inositol oxygenase
    CAG90181a Debaryomyces hansenii Phosphatidylinositol-specific phospholipase C
    BAD32688 Hansenula polymorpha Glycerol dehydrogenase
    BAD32689 Pichia ofunaensis Dihydroxyacetone reductase
    EAK93787 Candida albicans HGT1 High-affinity glucose transporter
    AAB17122 Debaryomyces occidentalis HAK1 High-affinity potassium transporter
    EAL02606 Candida albicans NUP Purine nucleoside permease
    EAK96574 Candida albicans UAP2 Potential purine permease
Lipid metabolism
    BAD11952 Saccharomyces kluyveri FAD3 ω-3 fatty acid desaturase
    AAU10084 Pichia pastoris Δ8-(E)-sphingolipid desaturase
    AAU10085 Pichia pastoris Δ4-(E)-sphingolipid desaturase
    AAZ08581 Ashbya gossypii Sphingolipid C9-methyltransferase
    AAK73020 Pichia pastoris Ceramide glucosyltransferase
Respiratory chain complexes
    CAG86996a Debaryomyces hansenii Complex I 14-kDa subunit
    CAG88782a Debaryomyces hansenii Complex I 20-kDa subunit
    CAG84577a Debaryomyces hansenii Complex I 24-kDa subunit
    CAG89146a Debaryomyces hansenii Complex I 49-kDa subunit
    CAG89064a Debaryomyces hansenii Complex I 51-kDa subunit
    CAG90271a Debaryomyces hansenii Complex I 75-kDa subunit
    CAG85893a Debaryomyces hansenii AOX1 SHAM-sensitive alternative terminal oxidase 1
    CAA82928 Hansenula polymorpha PER1 Peroxisomal matrix protein
    AAD52811 Hansenula polymorpha PEX1 Peroxin
    P78723 Hansenula polymorpha PEX14 Peroxin
    CAA65646 Pichia pastoris PEX2 Peroxin
    AAF19606 Pichia pastoris PEX17 Peroxin
    AAD43507 Pichia pastoris PEX19 Peroxin
    CAG60540a Candida glabrata PRN1 Putative pirin
    CAG85416a Debaryomyces hansenii URA9 Dihydroorotate dehydrogenase 2
    CAG86646a Debaryomyces hansenii Beta-alanine synthase
    CAH00925a Kluyveromyces lactis GTP cyclohydrolase II
    CAG80587a Yarrowia lipolytica FAD-dependent oxidoreductase
    BAB12222 Candida boidinii DAO1 d-Amino acid oxidase
    CAH02585 Kluyveromyces lactis Acid phosphatase
    AAS51137 Ashbya gossypii Calcineurin-like phosphoesterase
    EAL00803 Candida albicans Potential secreted Cu/Zn superoxide dismutase
    EAK95140 Candida albicans Possible thiamine biosynthesis enzyme
    EAL02572a Candida albicans Ras GTPase-activating protein
    CAG85348a Debaryomyces hansenii Potential histone binding protein
    CAG78240a Yarrowia lipolytica Translation initiation factor 3 subunit 7
    EAL04857 Candida albicans Negative regulator of iron uptake genes
    EAK96905 Candida albicans Potential fungal zinc cluster transcription factor
    AAQ75382 Hansenula polymorpha SWI1 Global transcription activator
  • a For this gene, the best BLAST hit of the D. bruxellensis sequence in the NR database is an unannotated or hypothetical gene, and the functional annotation given here is taken from the highest annotated hit, where the bit score of the annotated hit was at least 90% that of the best hit and sequence comparison indicates that the genes are homologs.