TABLE 4.

Gene families that are expanded in D. bruxellensis relative to both C. albicans and D. hansenii

Gene familyaS. cerevisiae genes in familyNo. of unique BLASTP hitsb
D. bruxellensisC. albicansD. hansenii
GLC.1379BNI1 BNR1422
GLC.1390ITC1 YPL216W211
GLC.1609DIN7 EXO1 RAD2 RAD27 YEN1544
GLC.1623SEC1 SLY1 VPS33 VPS45544
GLC.1700CDC46 CDC47 CDC54 MCM3 MCM6986
GLC.1702CDC16 CDC27433
GLC.1711RDS2 YBR239C YJL103C433
GLC.1749CCC2 DNF1 DNF2 DNF3 DRS2 ENA1 ENA2 ENA5 NEO1 PCA1 PMA1 PMA2 PMC1 PMR1 SPF1 YOR291W191818
GLC.1765NCL1 NOP2 YNL022C433
GLC.1826SHC1 SKT5311
GLC.1900ECM22 UPC2211
GLC.1967HSP26 HSP42200
GLC.2074GDE1 PHO81422
GLC.2091APL1 APL2 APL3 APL4 APL5 APL6 SEC26877
GLC.2291HMG1 HMG2 NCR1522
GLC.2339GEA1 GEA2 SEC7722
GLC.2379DHR2 ECM16 PRP16 PRP2 PRP22 PRP43 YLR419W1198
GLC.2424ARX1 MAP1 MAP2533
GLC.2529SCS3 YDR319C210
GLC.2545ACC1 HFA1643
  • a Gene families are from reference 19.

  • b Total number of unique BLASTP hits (with E values of <1e-10) of S. cerevisiae proteins in that family to each of the three species, respectively. Note that as the D. bruxellensis genome is not completely sequenced, the numbers of hits given for this species will be a substantial underestimate of the true figure.