TABLE 1.

T. brucei cell lines used in this study

Cell lineDrug resistance gene (BES location)Studied genes and transcription statusOriginal namea
ActiveSilent
PUR-VSG2 PUR (BES1) PUR, VSG2BF-LF17.9
NEO (BES7) NEO, VSG3
NEO-VSG3 PUR (BES1) PUR, VSG2BF-LF17.9s1.3
NEO (BES7) NEO, VSG3
PUR-VSG2(b) PUR (BES1) PUR, VSG2BF-LF17.21
NEO (BES4) NEO, VSG21
NEO-VSG21 PUR (BES1) PUR, VSG2BF-LF17.21s1
NEO (BES4) NEO, VSG21
PUR-VSG2(c) PUR (BES1) PUR, VSG2BF-LF17.13
NEO (BES17) NEO, VSG13
NEO-VSG13 PUR (BES1) PUR, VSG2BF-LF17.13s2
NEO (BES17) NEO, VSG13
  • a According to reference 10.