TABLE 2.

Growth phenotypes of Sre1-related hypoxia-sensitive mutants in the presence of ROS- or RNS-generating agents

Strain genotypeGrowth ona:
DEMH2O2MenadioneParaquatNaNO2Control, pH 4.0
sre1Δ 122213
sre1Δ SRE1 333333
scp1Δ 122213
scp1Δ SCP1 333333
sfb2Δ 111300
sfb2Δ SFB2 333333
stp1Δ 113212
stp1Δ STP1 233332
kap123Δ 231223
kap123Δ KAP123 332333
gsk3Δ 033313
gsk3Δ GSK3 333333
rsp5 121223
rsp5 RSP5 333333
dam1Δ 033333
dam1Δ DAM1 333333
  • a Scoring: 3, growth similar to wild type; 2, slight reduction in growth compared to wild type; 1, significant reduction in growth compared to wild type; 0, no growth.