TABLE 2.

Growth phenotypes of Sre1-related hypoxia-sensitive mutants in the presence of ROS- or RNS-generating agents

Strain genotypeGrowth ona:
DEMH2O2MenadioneParaquatNaNO2Control, pH 4.0
sre1Δ122213
sre1Δ SRE1333333
scp1Δ122213
scp1Δ SCP1333333
sfb2Δ111300
sfb2Δ SFB2333333
stp1Δ113212
stp1Δ STP1233332
kap123Δ231223
kap123Δ KAP123332333
gsk3Δ033313
gsk3Δ GSK3333333
rsp5121223
rsp5 RSP5333333
dam1Δ033333
dam1Δ DAM1333333
  • a Scoring: 3, growth similar to wild type; 2, slight reduction in growth compared to wild type; 1, significant reduction in growth compared to wild type; 0, no growth.