TABLE 3.

Functional categories of CGSa

DescriptionNo. of genes in functional category (%)b
Group AGroup BGroup C
Metabolism117 (15)194 (11.5)146 (13.5)
Energy28 (3.5)28 (1.7)29 (2.7)
Cell cycle and DNA processing31 (4)166 (9.8)116 (10.8)
Transcription65 (8)92 (5.4)54 (5)
Protein synthesis5 (0.5)32 (1.9)15 (1.4)
Protein fate34 (4)133 (7.8)136 (12.6)
Protein with binding function or cofactor requirement5 (0.5)10 (0.6)2 (0.1)
Protein activity regulation0.05 (0.3)5 (0.5)
Cell transport, transport facilitation, and transportation routes117 (15)163 (9.6)125 (11.6)
Cellular communication/signal transduction mechanism11 (1)20 (1.2)9 (0.8)
Cell rescue, defense, and virulence42 (5)45 (2.7)20 (1.9)
Interaction with the cellular environment15 (2)73 (4.3)32 (3)
Transposable elements, viral and plasmid proteins1 (0.1)2 (0.1)2 (0.2)
Cell fate19 (2)62 (3.7)24 (2.2)
Biogenesis of cellular components27 (3)101 (6)48 (4.5)
Cell type differentiation15 (2)79 (4.6)33 (3)
Subcellular localization2 (0.2)4 (0.2)0
Unclassified proteins102 (13)212 (12.5)120 (11)
No good homologies in S. cerevisiae161 (20)272 (16)165 (15)
  • a C. albicans ORFs or genes were assigned according to the MIPS classification of the S. cerevisiae homologues.

  • b Group A, ORFs with initial low fold change values that increased over time; group B, ORFs with constant fold change values; group C, ORFs with initial increased fold change values that later decreased.