TABLE 5.

Distribution of amino acid substitutions within the Sxi1α predicted homeodomain regiona

SXI1α allelic groupSubstitution at polymorphic amino acid site
−1127910111522283233373940434445
CN (consensus)FDNSPPIVDADFTGISQV
Ai (consensus)LHILSAPINADSYGMGKV
Aii··················
Aiii··················
Aiv··················
Av··················
Avi··················
Bi···S······E·HR·S··
Bii···S······E·HR·S··
Biii···S······E·HR·S··
Biv···S······E·HR·S··
C···S······E·HR·S··
D···S·····T·····S·I
  • a Residue 44, DNA-binding contact site (total of seven sites across region); CN, C. neoformans consensus sequence (JEC21); Ai, C. gattii (Ai) consensus sequence (WM276). Dots indicate that the residue corresponds to the Ai (consensus) residue.