TABLE 2.

Classification of genes into functional categoriesa

FunctionNo. (%) of transcripts induced
myo5Δ mutantbmyo5Δ-Y and sla2Δ-Y mutantscCyt A-treated genesdΔSH3ΔA mutante
Cell wall biogenesis17 (11)13 (16)0 (0)1 (4)
Membrane biogenesis8 (5)9 (11)1 (2)2 (4)
Membrane transport7 (5)3 (4)5 (8)3 (7)
Unknown membrane function7 (5)2 (2)3 (5)0 (0)
Protein trafficking and sorting12 (8)3 (4)0 (0)0 (0)
Endocytosis and actin elements5 (3)1 (1)0 (0)1 (2)
Multidrug resistance0 (0)1 (1)3 (5)2 (4)
Stress and redox14 (9)10 (12)14 (23)1 (2)
Protein folding and degradation6 (4)1 (1)9 (15)2 (4)
Iron metabolism4 (3)1 (1)0 (0)0 (0)
Metabolism20 (13)10 (12)12 (19)22 (42)
Miscellaneous18 (12)6 (7)7 (11)9 (16)
Unknown33 (22)21 (26)8 (13)8 (15)
Total151816251
  • a Table 2 is based on data presented in Tables S1, S2, and S3 at http://candida.bri.nrc.ca/papers/myo/.

  • b Commonly identified transcripts in the myo5Δ mutant, obtained using amplicon and oligonucleotide microarrays.

  • c Commonly identified transcripts in the myo5Δ-Y and sla2Δ-Y mutants.

  • d Transcripts unique to cytochalasin A (Cyt A)-treated genes and not identified in the myo5Δ and sla2Δ mutants.

  • e Transcripts unique to the ΔSH3ΔA mutant and not identified in the myo5Δ and sla2Δ mutants; these may also have been identified under cytochalasin A treatment conditions.