TABLE 6.

Genes downregulated by the G648D mutation in Upc2p

CandidaDB nameaCommon nameborf19 no.cGO annotation (molecular function)dFold decrease in expression
S2 vs S1UPC2S2-1 vs UPC2S1-1
Strain AStrain B
Expt 1Expt 2Expt 1Expt 2Expt 1Expt 2
COQ1orf19.7478trans-Hexaprenyltranstransferase activity−2.8−2.9−1.5−2.5−2.4−3.8
MAS2orf19.6295Mitochondrial processing peptidase activity−1.6−1.7−1.6−2.3−2.7−2.9
MET14MET14orf19.946Adenylylsulfate kinase activity−5.6−6.9−2.3−2.9−3.5−3.7
MET3MET3orf19.5025Sulfate adenylyltransferase (ATP) activity−4.2−3.8−3.3−4.0−3.5−5.9
PET127orf19.2309RNA binding−1.7−1.8−2.0−4.4−7.7−5.9
IPF11801orf19.2798Helicase activity−1.6−1.7−2.3−2.2−2.0−1.8
IPF14872orf19.4133−2.0−1.8−1.8−3.5−2.3−4.0
IPF20118orf19.3846−3.8−4.4−3.6−3.1−1.7−1.6
IPF525orf19.7085−2.4−2.2−1.7−3.1−1.7−1.7
IPF6504orf19.1544−2.1−2.0−1.8−1.5−1.7−1.6
IPF7334orf19.3724−2.3−2.2−1.6−3.1−1.8−3.4