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Articles

Rapamycin Exerts Antifungal Activity In Vitro and In Vivo against Mucor circinelloides via FKBP12-Dependent Inhibition of Tor

Robert J. Bastidas, Cecelia A. Shertz, Soo Chan Lee, Joseph Heitman, Maria E. Cardenas
Robert J. Bastidas
aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
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Cecelia A. Shertz
aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
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Soo Chan Lee
aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
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Joseph Heitman
aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
bMedicine, Duke University Medical Center, Durham, North Carolina, USA
cPharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA
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Maria E. Cardenas
aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
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DOI: 10.1128/EC.05284-11
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Article Information

DOI 
https://doi.org/10.1128/EC.05284-11
PubMed 
22210828

Published By 
American Society for Microbiology Journals
History 
  • Received November 2, 2011
  • Accepted December 22, 2011
  • Published online February 28, 2012.

Copyright & Usage 
Copyright © 2012, American Society for Microbiology. All Rights Reserved.

Article Versions

  • Accepted Manuscript version (December 30, 2011).
  • You are viewing the most recent version of this article.

Author Information

  1. Robert J. Bastidasa,
  2. Cecelia A. Shertza,
  3. Soo Chan Leea,
  4. Joseph Heitmana,b,c and
  5. Maria E. Cardenasa
  1. aDepartments of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA
  2. bMedicine, Duke University Medical Center, Durham, North Carolina, USA
  3. cPharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA
  • Address correspondence to Maria E. Cardenas, carde004{at}mc.duke.edu.
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Rapamycin Exerts Antifungal Activity In Vitro and In Vivo against Mucor circinelloides via FKBP12-Dependent Inhibition of Tor
Robert J. Bastidas, Cecelia A. Shertz, Soo Chan Lee, Joseph Heitman, Maria E. Cardenas
Eukaryotic Cell Feb 2012, 11 (3) 270-281; DOI: 10.1128/EC.05284-11

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Rapamycin Exerts Antifungal Activity In Vitro and In Vivo against Mucor circinelloides via FKBP12-Dependent Inhibition of Tor
Robert J. Bastidas, Cecelia A. Shertz, Soo Chan Lee, Joseph Heitman, Maria E. Cardenas
Eukaryotic Cell Feb 2012, 11 (3) 270-281; DOI: 10.1128/EC.05284-11
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