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Cover photograph (Copyright © 2008, American Society for Microbiology. All Rights Reserved.): Amyloid fiber aggregates formed by a 13-amino-acid peptide sequence conserved in Candida albicans Als adhesins. Amyloid fibers also formed from 412-residue and 645-residue N-terminal regions of the adhesin Als5p. The Als adhesins mediate adherence of the yeast to host tissues and to other microbes, as well as aggregating C. albicans cells. (Negative-stained transmission electron micrograph; bar, 500 nm.) (See related article on page 776.)


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