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Cover photograph (Copyright © 2008, American Society for Microbiology. All Rights Reserved.): Chitinlike oligomers connect cell wall and capsular components of Cryptococcus neoformans. Staining of capsular structures with a monoclonal antibody (green), cell wall chitin with calcofluor white (blue), and chitin-derived oligomers with the wheat germ lectin (wheat germ agglutinin [WGA]) (red) followed by confocal analysis reveals that round or hook-like projections recognized by WGA connect the cell wall and the capsule. This analysis reveals a new molecular mechanism by which capsular components interact with cell wall elements in C. neoformans. (See related article on page 602.)
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