Cover photograph (Copyright © 2006, American Society for Microbiology. All Rights Reserved.): Scanning electron microscopy images of a Trypanosoma brucei galactose epimerase conditional null mutant before galactose starvation (upper panel) and after 96 h of galactose starvation (lower panel). (Images acquired by Martin Kierans of the Centre for High Resolution Imaging and Processing at the University of Dundee, United Kingdom.) (See related article on page 1906.)