Cover photograph (Copyright © 2005, American Society for Microbiology. All Rights Reserved.): Immunofluorescence of Cryptococcus neoformans H99 cells subjected to different treatments and stained with glucuronoxylomannan-specific monoclonal antibody 2H1. Left panels, light microscopy images; right panels, fluorescence images. Top, untreated; middle, gamma radiation; bottom, dimethyl sulfoxide. (See related article on page 465.)