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 Previous Article

Eukaryotic Cell, February 2009, p. 257-260, Vol. 8, No. 2
1535-9778/09/$08.00+0     doi:10.1128/EC.00348-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.

Uncoupling of the Patterns of Chromatin Association of Different Transcription Elongation Factors by a Histone H3 Mutant in Saccharomyces cerevisiae{triangledown}

Amanda Lloyd, Katie Pratt, Erica Siebrasse, Matthew D. Moran, and Andrea A. Duina*

Biology Department, Hendrix College, Conway, Arkansas

Received 17 October 2008/ Accepted 20 November 2008

The transcription elongation complexes yFACT, Spt4/Spt5, and Spt6/Iws1 were previously shown to follow similar patterns of association across transcribed genes in Saccharomyces cerevisiae. Using a histone H3 mutant, we now provide evidence that the mechanism of association of yFACT across genes is separable from that adopted by Spt4/Spt5 and Spt6/Iws1.

* Corresponding author. Mailing address: Biology Department, Hendrix College, 1600 Washington Avenue, Conway, AR 72032. Phone: (501) 450-4536. Fax: (501) 450-4547. E-mail: duina{at}hendrix.edu

{triangledown} Published ahead of print on 1 December 2008.

Eukaryotic Cell, February 2009, p. 257-260, Vol. 8, No. 2
1535-9778/09/$08.00+0     doi:10.1128/EC.00348-08
Copyright © 2009, American Society for Microbiology. All Rights Reserved.





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