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 Previous Article

Eukaryotic Cell, October 2002, p. 843-845, Vol. 1, No. 5
1535-9778/02/$04.00+0     DOI: 10.1128/EC.1.5.843-845.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.

Role of Fig2p in Agglutination in Saccharomyces cerevisiae

Chong K. Jue and Peter N. Lipke*

Department of Biological Sciences and the Center for Gene Structure and Function, Hunter College, City University of New York, New York, New York 10021

Received 5 March 2002/ Accepted 20 May 2002

In W303-derived strains, disruption of FIG2 increased agglutinability of {alpha} cells, but not a cells, and did not alter expression of {alpha}-agglutinin, binding of 125I-labeled {alpha}-agglutinin, or mating efficiency. Fig2p overexpression led to {alpha}-cell-specific suppression of agglutinability. These results imply that Fig2p is an indirect masker of the active sites in {alpha}-agglutinin.

* Corresponding author. Mailing address: Department of Biological Sciences, Hunter College, 695 Park Ave., New York, NY 10021. Phone: (212) 772-5235. Fax: (212) 772-5227. E-mail: lipke{at}genectr.hunter.cuny.edu.

Eukaryotic Cell, October 2002, p. 843-845, Vol. 1, No. 5
1535-9778/02/$04.00+0     DOI: 10.1128/EC.1.5.843-845.2002
Copyright © 2002, American Society for Microbiology. All Rights Reserved.



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