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FIG. 2. Response to iron deprivation in Saccharomyces cerevisiae. Proteins under the transcriptional control of Aft1p and Aft2p are labeled with black text. Ccc1p, proteins of the tricarboxylic acid cycle, the respiratory cytochromes, and the glutamate, heme, and biotin biosynthetic pathways are down-regulated during iron deficiency and are indicated with gray text.
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