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Eukaryotic Cell, March 2008, p. 546-549, Vol. 7, No. 3
1535-9778/08/$08.00+0 doi:10.1128/EC.00437-07
Copyright © 2008, American Society for Microbiology. All Rights Reserved.

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110
Received 30 November 2007/ Accepted 17 December 2007
The fungal pathogen Cryptococcus neoformans regulates its polysaccharide capsule depending on environmental stimuli. To investigate whether capsule polymers change under different growth conditions, we analyzed shed capsules at physiological concentrations without physical perturbation. Our results indicate that regulation of capsule size is mediated at the level of individual polysaccharide molecules.
Published ahead of print on 21 December 2007.
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