Eukaryotic Cell
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Eukaryotic Cell, September 2005, p. 1591-1594, Vol. 4, No. 9
1535-9778/05/$08.00+0     doi:10.1128/EC.4.9.1591-1594.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Characterization of a Molecular Chaperone Present in the Eukaryotic Flagellum

Jessica Shapiro,{dagger} Jessica Ingram,{ddagger} and Karl A. Johnson*

Department of Biology, Haverford College, Haverford, Pennsylvania 19041

Received 8 April 2005/ Accepted 22 June 2005

Chlamydomonas flagella contain a molecular chaperone now identified as HSP70A, a major cytoplasmic isoform. HSP70A synthesis is upregulated by deflagellation, and its distribution in the flagellum overlaps with the IFT kinesin-II motor FLA10. HSP70A may chaperone flagellar proteins during transport, participating in the assembly and maintenance of the flagellum.

* Corresponding author. Mailing address: Department of Biology, Haverford College, 370 Lancaster Ave., Haverford, PA 19041. Phone: (610) 896-1306. Fax: (610) 896-4963. E-mail: kjohnson{at}haverford.edu.

{dagger} Present address: Stanford University, Department of Genetics, Stanford, CA 94305.

{ddagger} Present address: New England Biolabs, Inc., Beverly, MA 01915.

Eukaryotic Cell, September 2005, p. 1591-1594, Vol. 4, No. 9
1535-9778/05/$08.00+0     doi:10.1128/EC.4.9.1591-1594.2005
Copyright © 2005, American Society for Microbiology. All Rights Reserved.





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