Eukaryotic Cell
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Eukaryotic Cell, April 2004, p. 564-566, Vol. 3, No. 2
1535-9778/04/$08.00+0     DOI: 10.1128/EC.3.2.564-566.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.

Identification of Genes Dependent on the MADS Box Transcription Factor SrfA in Dictyostelium discoideum Development{dagger}

Ricardo Escalante,1 Negin Iranfar,2 Leandro Sastre,1* and William F. Loomis2

Instituto de Investigaciones Biomédicas CSIC/UAM, 28029 Madrid, Spain,1 Cell and Developmental Biology, Division of Biology, University of California at San Diego, La Jolla, California 920932

Received 13 November 2003/ Accepted 12 January 2004

Analysis of microarrays containing 6,345 Dictyostelium discoideum genes has identified 21 whose expression is dependent on the MADS box transcription factor SrfA. In wild-type cells, all of these genes are induced late in development. At least four of them are necessary for proper spore differentiation, stability, and/or germination.

* Corresponding author. Mailing address: Instituto de Investigaciones Biomédicas, CSIC/UAM, Arturo Duperier, 4, 28029 Madrid, Spain. Phone: 34 91 585 4437. Fax: 34 91 585 4401. E-mail: lsastre{at}iib.uam.es.

{dagger} Supplemental material for this article may be found at http://ec.asm.org/.

Eukaryotic Cell, April 2004, p. 564-566, Vol. 3, No. 2
1535-9778/04/$08.00+0     DOI: 10.1128/EC.3.2.564-566.2004
Copyright © 2004, American Society for Microbiology. All Rights Reserved.



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