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 Previous Article

Eukaryotic Cell, June 2003, p. 651-653, Vol. 2, No. 3
1535-9778/03/$08.00+0     DOI: 10.1128/EC.2.3.651-653.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.

Evidence that Synthesis of the Saccharomyces cerevisiae Mitochondrially Encoded Ribosomal Protein Var1p May Be Membrane Localized

Alessandro Fiori,1 Thomas L. Mason,2 and Thomas D. Fox1*

Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853,1 Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, Massachusetts 010032

Received 16 January 2003/ Accepted 14 March 2003

The 5'-untranslated leaders of mitochondrial mRNAs appear to localize translation within the organelle. VAR1 is the only yeast mitochondrial gene encoding a major soluble protein. A chimeric mRNA bearing the VAR1 untranslated regions and the coding sequence for pre-Cox2p appears to be translated at the inner membrane surface. We propose that translation of the ribosomal protein Var1p is also likely to occur in close proximity to the inner membrane.

* Corresponding author. Mailing address: Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853. Phone: (607) 254-4835. Fax: (607) 255-6249. E-mail: tdf1{at}cornell.edu.

Eukaryotic Cell, June 2003, p. 651-653, Vol. 2, No. 3
1535-9778/03/$08.00+0     DOI: 10.1128/EC.2.3.651-653.2003
Copyright © 2003, American Society for Microbiology. All Rights Reserved.



This article has been cited by other articles:

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